FindAlmostNullomers


Identifies all possible single base pair substitutions, insertions, or deletions, genome-wide that cause the resurfacing of at least one nullomer.



Required arguments:

Argument

Explanation

–genome_filepath

Path to the fasta file containing the genome being analyzed.*

–nullomer_input_filepath

Path to the .txt file containing the nullomers absent from the supplied genome.

–nullomer_output_filepath

Path to the output .txt file where the nullomers absent from the supplied genome will be written, with one nullomer written on each line.

—nullomer_length

Length of nullomers being analyzed.



Outputs:

  • VCF-compatible file containing all variants genome-wide that cause at least one nullomer to resurface.